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Article

Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells

1 Jan 2013

Abstract excerpt

Foetal development of germ cells is a unique biological process orchestrated by cellular specification, migration and niche development in concert with extensive epigenetic and transcriptional programs. Many of these processes take place early in foetal life and are hence very difficult to study in humans. However, the common precursor of testicular cancers- the carcinoma in situ (CIS) cell- is thought to be an...

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PMID: 23784842
DOI: 10.1387/ijdb.130142ka

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