Article
The emerging phenotype of the testicular carcinoma in situ germ cell.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2003
Rajpert-De Meyts Ewa, Bartkova Jirina, Samson Michel, Hoei-Hansen Christina E, Frydelund-Larsen Lone, Bartek Jiri, Skakkebaek Niels E
Abstract excerpt
This review summarises the existing knowledge on the phenotype of the carcinoma in situ (CIS) cell. CIS is a common pre-invasive precursor of testicular germ cell tumours of adolescents and young adults. These tumours display a variety of histological forms. Classical seminoma proliferates along the germ cell lineage, whereas embryonal carcinoma retains embryonic features and readily differentiates into teratomas...
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