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Article

The biology of germ cell tumors in disorders of sex development.

Clinical genetics - 1 Feb 2017

Hersmus Remko, van Bever Yolande, Wolffenbuttel Katja P, Biermann Katharina, Cools Martine, Looijenga Leendert H J

Abstract excerpt

Development of a malignant germ cell tumor, i.e., germ cell cancer (GCC) in individuals with disorders of sex development (DSD) depends on a number of (epi-)genetic factors related to early gonadal- and germ cell development, possibly related to genetic susceptibility. Fetal development of germ cells is orchestrated by strict processes involving specification, migration and the development of a proper gonadal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27716895
DOI: 10.1111/cge.12882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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