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Epigenetics and Testicular Cancer: Bridging the Gap Between Fundamental Biology and Patient Care

8 Apr 2022

Abstract excerpt

Testicular cancer is the most common solid tumor affecting young males. Most testicular cancers are testicular germ cell tumors (TGCTs), which are divided into seminomas (SGCTs) and non-seminomatous testicular germ cell tumors (NSGCTs). During their development, primordial germ cells (PGCs) undergo epigenetic modifications and any disturbances in their pattern might lead to cancer development. The present study...

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PMID: 35465311
DOI: 10.3389/fcell.2022.861995

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