Article
Maturation or differentiation of human thymocyte precursors in vitro?
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
Groh V, Fabbi M, Strominger J L
Abstract excerpt
The differentiation or maturation potential of human thymocyte precursors has been studied by using a population of CD3/TCR-, CD4-, CD8- ("triple negative") thymocytes isolated by negative selection (TCR, T-cell receptor). This cell population, however, also contained 30-50% previously undescribed cells expressing very low levels of CD3/TCR gamma delta (CD3/TCR gamma delta low; approximately 60% of which...
Topics
- Antibodies, Monoclonal
- Antigens, CD
- Blotting, Southern
- Cell Differentiation
- Cell Line
- Child
- Gene Rearrangement, T-Lymphocyte
- Humans
- In Vitro Techniques
- Lymphocyte Depletion
- Phenotype