Article
Development of dendritic cells in culture from human and murine thymic precursor cells.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 Feb 2001
Kelly K A, Lucas K, Hochrein H, Metcalf D, Wu L, Shortman K
Abstract excerpt
The earliest T-precursor population in the adult murine thymus can give rise to dendritic cells (DC) in culture if stimulated with a cocktail of cytokines that includes interleukin (IL)-3, but not with cytokine mixes based on granulocyte-macrophage colony stimulating factor (GM-CSF), normally used to generate myeloid-derived DC. This and other evidence led to the proposal that two different lineages of DC exist,...
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