Article
Development of a method of thymocyte differentiation of bone marrow-enriched CD34+CD38- cells in postnatal allogeneic cultured thymic epithelia to evaluate immunodeficiency disorders.
Stem cells (Dayton, Ohio) - 1 Nov 1996
Knutsen A P, Roodman S T, Ruiz M E, Mueller K R, Bouhasin J D
Abstract excerpt
An in vitro model of CD34+CD38- stem cell (SC) differentiation in postnatal cultured thymic epithelia fragment (CTEF) cocultures is described. Sequential phenotypic analysis of the progeny of the SC-CTEF demonstrated predominantly thymocytes and minor populations of promyelocytes, monocytes and n...
Topics
- ADP-ribosyl Cyclase
- ADP-ribosyl Cyclase 1
- Antigens, CD
- Antigens, CD34
- Antigens, Differentiation
- Bone Marrow Cells
- Cell Differentiation
- Epithelial Cells
- Epithelium
- Flow Cytometry
- HIV Infections
- Humans
- Hyaluronan Receptors
- Membrane Glycoproteins