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Article

Genetic polymorphisms in RAD23B and XPC modulate DNA repair capacity and breast cancer risk in Puerto Rican women.

Molecular carcinogenesis - 1 Nov 2013

Pérez-Mayoral Julyann, Pacheco-Torres Alba L, Morales Luisa, Acosta-Rodríguez Heidi, Matta Jaime L, Dutil Julie

Abstract excerpt

Studies have shown that DNA repair capacity (DRC) is significantly decreased in breast cancer patients, but the molecular causes of inter-individual variation in DRC are unknown. We hypothesized that genetic variation in the nucleotide excision repair pathway genes can modulate DRC and breast cancer risk in Puerto Rican women. A total of 228 breast cancer cases and 418 controls were recruited throughout Puerto...

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Identifiers

PMID: 23776089
DOI: 10.1002/mc.22056
PMCID: PMC4104768

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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