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Article

Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study.

Carcinogenesis - 1 Jul 2006

Mechanic Leah E, Millikan Robert C, Player Jon, de Cotret Allan René, Winkel Scott, Worley Kendra, Heard Kristin, Heard Kimberley, Tse Chiu-Kit, Keku Temitope

Abstract excerpt

Polymorphisms exist in several genes involved in nucleotide excision repair (NER), the principal pathway for removal of smoking-induced DNA damage. An epidemiologic study was conducted to determine whether these polymorphisms modify the association between smoking and breast cancer. DNA samples and exposure histories were analyzed as part of a large population-based case-control study of breast cancer in North...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16399771
DOI: 10.1093/carcin/bgi330

Genes

ERCC6
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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