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Article

Endothelial nitric oxide synthase gene polymorphisms and the risk of osteonecrosis of the femoral head in systemic lupus erythematosus.

International orthopaedics - 1 Nov 2013

Kim Hak Soo, Bae Sang-Cheol, Kim Tae-Ho, Kim Shin-Yoon

Abstract excerpt

PURPOSE: Nitric oxide (NO), a short-lived gaseous free radical, is a potent mediator of biological responses involved in the pathogenesis of autoimmune rheumatic diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Nitric oxide also serves as an important signal in physiological processes, including angiogenesis, thrombosis, and bone turnover, which are known to be related to the...

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Identifiers

PMID: 23775455
DOI: 10.1007/s00264-013-1966-6
PMCID: PMC3824903

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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