Article
Novel susceptibility loci for steroid-associated osteonecrosis of the femoral head in systemic lupus erythematosus.
Human molecular genetics - 31 Mar 2022
Suetsugu Hiroyuki, Kim Kwangwoo, Yamamoto Takuaki, Bang So-Young, Sakamoto Yuma, Shin Jung-Min, Sugano Nobuhiko, Kim Ji Soong, Mukai Masaya, Lee Yeon-Kyung, Ohmura Koichiro, Park Dae Jin, Takahashi Daisuke, Ahn Ga-Young, Karino Kohei, Kwon Young-Chang, Miyamura Tomoya, Kim Jihye, Nakamura Junichi, Motomura Goro, Kuroda Takeshi, Niiro Hiroaki, Miyamoto Takeshi, Takeuchi Tsutomu, Ikari Katsunori, Amano Koichi, Tada Yoshifumi, Yamaji Ken, Shimizu Masato, Atsumi Takashi, Seki Taisuke, Tanaka Yoshiya, Kubo Toshikazu, Hisada Ryo, Yoshioka Tomokazu, Yamazaki Mihoko, Kabata Tamon, Kajino Tomomichi, Ohta Yoichi, Okawa Takahiro, Naito Yohei, Kaneuji Ayumi, Yasunaga Yuji, Ohzono Kenji, Tomizuka Kohei, Koido Masaru, Matsuda Koichi, Okada Yukinori, Suzuki Akari, Kim Bong-Jo, Kochi Yuta, Lee Hye-Soon, Ikegawa Shiro, Bae Sang-Cheol, Terao Chikashi
Abstract excerpt
Osteonecrosis of the femoral head (ONFH) involves necrosis of bone and bone marrow of the femoral head caused by ischemia with unknown etiology. Previous genetic studies on ONFH failed to produce consistent results, presumably because ONFH has various causes with different genetic backgrounds and the underlying diseases confounded the associations. Steroid-associated ONFH (S-ONFH) accounts for one-half of all...
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