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Article

Investigation and analysis of single nucleotide polymorphisms in Janus kinase/signal transducer and activator of transcription genes with leukemia.

Leukemia & lymphoma - 1 Jun 2012

Zhong Yuejiao, Wu Jianzhong, Chen Baoan, Ma Rong, Cao Haixia, Wang Zhuo, Cheng Lu, Ding Jiahua, Feng Jifeng

Abstract excerpt

Aberrant activation of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway may predispose to leukemia due to deregulation of proliferation, differentiation or apoptosis. This study was conducted to investigate whether any association exists between genetic polymorphisms in the JAK2, STAT3 and STAT5 genes and individual susceptibility to leukemia. A case-control study was carried...

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Source

Identifiers

PMID: 22126101
DOI: 10.3109/10428194.2011.645212

Genes

STAT3
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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