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Propranolol reduces cognitive deficits, amyloid and tau pathology in Alzheimer's transgenic mice.

The international journal of neuropsychopharmacology - 1 Nov 2013

Dobarro Marta, Gerenu Gorka, Ramírez María J

Abstract excerpt

The efficacy of antihypertensive agents in Alzheimer's disease (AD) is controversial. It has been tested here whether some antihypertensive drugs might influence AD through mechanisms independent of blood pressure-lowering activity. The effects of treatment with the antihypertensive propranolol on cognition and AD-related markers have been studied in the Tg2576 mouse model of AD. Propranolol, at a lower dose than...

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PMID: 23768694
DOI: 10.1017/S1461145713000631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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