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Cannabinoid Type 1 Receptor Antagonist Impaired Spatial Memory and Increased the Tau Gene Expression in Animal Model of the Alzheimer's disease

2023-09-12

Abstract excerpt

Alzheimer's disease is a neurodegenerative disease characterized by the accumulation of two different proteins, β-amyloid and tau. The present study aimed to scrutinize the effects of bilateral administration of the cannabinoid receptor antagonist (AM251) in the hippocampus on spatial memory and tau gene expression in an Alzheimer's disease model. β-amyloid toxin was injected bilaterally into the hippocampus of Wi...

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Literature Corpus work
36485e0c-4b59-53be-a17a-dd036bb0b25b
DOI
10.21203/rs.3.rs-3332329/v1
Open publication

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Cannabinoid Type 1 Receptor Antagonist Impaired Spatial Memory and Increased the Tau Gene Expression in Animal Model of the Alzheimer's diseaseDOI 10.21203/rs.3.rs-3332329/v1
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