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Article

Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations.

American journal of human genetics - 11 Jul 2013

Ko Wen-Ya, Rajan Prianka, Gomez Felicia, Scheinfeldt Laura, An Ping, Winkler Cheryl A, Froment Alain, Nyambo Thomas B, Omar Sabah A, Wambebe Charles, Ranciaro Alessia, Hirbo Jibril B, Tishkoff Sarah A

Abstract excerpt

Disease susceptibility can arise as a consequence of adaptation to infectious disease. Recent findings have suggested that higher rates of chronic kidney disease (CKD) in individuals with recent African ancestry might be attributed to two risk alleles (G1 and G2) at the serum-resistance-associate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein L1

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Share to Lipoproteins, HDL

Share to Renal Insufficiency, Chronic

Share to Trypanosomiasis, African

Source

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Identifiers

PMID: 23768513
DOI: 10.1016/j.ajhg.2013.05.014
PMCID: PMC3710747

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23768513-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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