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Article

A Brief History of APOL1: A Gene Evolving.

Seminars in nephrology - 1 Nov 2017

Friedman David J

Abstract excerpt

APOL1 kidney risk variants lead to high rates of kidney disease in people of recent African ancestry. These risk variants are very common and confer a large increase in risk of kidney disease. This unusual combination of high frequency and large effect size occurs because the risk variants also appear to have beneficial properties. The risk variants show enhanced protective effects against certain pathogens,...

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Share to Apolipoprotein L1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29110757
DOI: 10.1016/j.semnephrol.2017.07.003

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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