Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors.

Journal of the American Society of Nephrology : JASN - 1 Sept 2013

Hendry Caroline E, Vanslambrouck Jessica M, Ineson Jessica, Suhaimi Norseha, Takasato Minoru, Rae Fiona, Little Melissa H

Abstract excerpt

Direct reprogramming involves the enforced re-expression of key transcription factors to redefine a cellular state. The nephron progenitor population of the embryonic kidney gives rise to all cells within the nephron other than the collecting duct through a mesenchyme-to-epithelial transition, bu...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Epithelial-Mesenchymal Transition
Share to HEK293 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Kidney Tubules, Proximal

Share to Nephrons

Share to Snail Family Transcription Factors

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 23766537
DOI: 10.1681/ASN.2012121143
PMCID: PMC3752949

Genes

SNAI2
EYA1
HOXA11
OSR1
SIX1
SIX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23766537-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors.PMID 23766537Read ↗

Fate-mapping within human kidney organoids reveals conserved mammalian nephron progenitor lineage relationshipsSemantic proximity Read ↗

A coordinated progression of progenitor cell states initiates urinary tract developmentSemantic proximity Read ↗

Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1Semantic proximity Read ↗

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney DevelopmentSemantic proximity Read ↗

Generation of multi-lineage kidney assembloids with integration between nephrons and a single exiting collecting ductSemantic proximity Read ↗

Direct Isolation and Characterization of Human Nephron Progenitors.Semantic proximity Read ↗

Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulatorsSemantic proximity Read ↗

A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem CellsSemantic proximity Read ↗

Notch signaling promotes nephrogenesis by downregulating Six2Semantic proximity Read ↗

Reprogramming the kidney: a novel approach for regeneration.Semantic proximity Read ↗

Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric budSemantic proximity Read ↗

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse KidneySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.