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Article

Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors.

Journal of the American Society of Nephrology : JASN - 1 Sept 2013

Hendry Caroline E, Vanslambrouck Jessica M, Ineson Jessica, Suhaimi Norseha, Takasato Minoru, Rae Fiona, Little Melissa H

Abstract excerpt

Direct reprogramming involves the enforced re-expression of key transcription factors to redefine a cellular state. The nephron progenitor population of the embryonic kidney gives rise to all cells within the nephron other than the collecting duct through a mesenchyme-to-epithelial transition, but this population is exhausted around the time of birth. Here, we sought to identify the conditions under which adult...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23766537
DOI: 10.1681/ASN.2012121143
PMCID: PMC3752949

Genes

SNAI2
EYA1
HOXA11
OSR1
SIX1
SIX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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