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Article

A human FSHB promoter SNP associated with low FSH levels in men impairs LHX3 binding and basal FSHB transcription.

Endocrinology - 1 Sept 2013

Benson Courtney A, Kurz Troy L, Thackray Varykina G

Abstract excerpt

FSH production is important for human gametogenesis. In addition to inactivating mutations in the FSHB gene, which result in infertility in both sexes, a G/T single-nucleotide polymorphism (SNP) at -211 relative to the transcription start site of the 5' untranslated region of FSHB has been reported to be associated with reduced serum FSH levels in men. In this study, we sought to identify the potential mechanism...

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Source

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Identifiers

PMID: 23766128
DOI: 10.1210/en.2013-1294
PMCID: PMC3749480

Genes

FSHB
LHX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A human FSHB promoter SNP associated with low FSH levels in men impairs LHX3 binding and basal FSHB transcription.PMID 23766128Read ↗

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