Article
Vascular endothelial growth factor induces multidrug resistance-associated protein 1 overexpression through phosphatidylinositol-3-kinase /protein kinase B signaling pathway and transcription factor specificity protein 1 in BGC823 cell line.
Acta biochimica et biophysica Sinica - 1 Aug 2013
Li Juan, Wu Xiaojun, Gong Jinling, Yang Jing, Leng Jiayan, Chen Qiaoyun, Xu Wenlin
Abstract excerpt
Multidrug resistance (MDR) is one of the most important causes of chemotherapy failure and carcinoma recurrence. But the roles of the MDR-associated protein MRP1 in MDR remain poorly understood. Vascular endothelial growth factor (VEGF), one of the most active and specific vascular growth factors...
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