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Molecular and functional MDR1‐Pgp and MRPs expression in human glioblastoma multiforme cell lines

14 Feb 2002

Abstract excerpt

The aim of our study was to investigate the functional expression of P-glycoprotein (Pgp) and multidrug resistance-associated proteins (MRPs) in 2 distinct glioma cells (GL15 and 8MG) from patients with glioblastoma multiforme. MDR1 gene and Pgp expression was not detected in either cell line by RT-PCR and Western blotting, respectively. In contrast, MRP1 was detected at both mRNA and protein level in both cell...

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PMID: 11857404
DOI: 10.1002/ijc.10135

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