Article
[Establishment of MRP-overexpression subline of bladder carcinoma and its MDR phenotype].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 2000
Zhang X, Yang H, Lu G
Abstract excerpt
OBJECTIVE: To investigate MRP expression and multidrug resistance(MDR) phenotype of a bladder carcinoma subline transfected with the full length MRP cDNA. METHODS: After transfection, a stable MRP-overexpressed subline named EJ/MRP was established. Gene expression of MRP and mdr1 were detected by using RT-PCR and immunohistochemistry methods. Drug sensitivity testing of the EJ/MRP cells to 11 kinds of anti-cancer...
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