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Article

Case-control association testing of common variants from sequencing of DNA pools.

PloS one - 1 Jan 2013

McRae Allan F, Richter Melinda M, Lind Penelope A

Abstract excerpt

While genome-wide association studies (GWAS) have been successful in identifying a large number of variants associated with disease, the challenge of locating the underlying causal loci remains. Sequencing of case and control DNA pools provides an inexpensive method for assessing all variation in a genomic region surrounding a significant GWAS result. However, individual variants need to be ranked in terms of the...

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PMID: 23762362
DOI: 10.1371/journal.pone.0065410
PMCID: PMC3676437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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