Article
Overlapping pools for high-throughput targeted resequencing.
Genome research - 1 Jul 2009
Prabhu Snehit, Pe'er Itsik
Abstract excerpt
Resequencing genomic DNA from pools of individuals is an effective strategy to detect new variants in targeted regions and compare them between cases and controls. There are numerous ways to assign individuals to the pools on which they are to be sequenced. The naïve, disjoint pooling scheme (man...
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