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Article

Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55.

PloS one - 1 Jan 2013

Ozhand Ali, Lee Eunjung, Wu Anna H, Ellingjord-Dale Merete, Akslen Lars A, McKean-Cowdin Roberta, Ursin Giske

Abstract excerpt

BACKGROUND: Mammographic density (MD) has been found to be an independent risk factor for breast cancer. Although data from twin studies suggest that MD has a strong genetic component, the exact genes involved remain to be identified. Alterations in stromal composition and the number of epithelial cells are the most predominant histopathological determinants of mammographic density. Interactions between the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23762340
DOI: 10.1371/journal.pone.0065313
PMCID: PMC3676419

Genes

FGFR2
IGFBP1
IGFBP3
TGFB1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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