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Article

Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users.

Breast cancer research : BCR - 27 Oct 2012

Ellingjord-Dale Merete, Lee Eunjung, Couto Elisabeth, Ozhand Ali, Qureshi Samera, Hofvind Solveig, Van Den Berg David J, Akslen Lars A, Grotmol Tom, Ursin Giske

Abstract excerpt

INTRODUCTION: Mammographic density (MD) is one of the strongest known breast cancer risk factors. Estrogen and progestin therapy (EPT) has been associated with increases in MD. Dense breast tissue is characterized by increased stromal tissue and (to a lesser degree) increased numbers of breast epithelial cells. It is possible that genetic factors modify the association between EPT and MD, and that certain genetic...

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Source

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Identifiers

PMID: 23095343
DOI: 10.1186/bcr3337
PMCID: PMC4053113

Genes

PRL
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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