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Article

graph-GPA: A graphical model for prioritizing GWAS results and investigating pleiotropic architecture.

PLoS computational biology - 1 Feb 2017

Chung Dongjun, Kim Hang J, Zhao Hongyu

Abstract excerpt

Genome-wide association studies (GWAS) have identified tens of thousands of genetic variants associated with hundreds of phenotypes and diseases, which have provided clinical and medical benefits to patients with novel biomarkers and therapeutic targets. However, identification of risk variants associated with complex diseases remains challenging as they are often affected by many genetic variants with small or...

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Identifiers

PMID: 28212402
DOI: 10.1371/journal.pcbi.1005388
PMCID: PMC5347371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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