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Article

The polymorphisms in the MGMT gene and the risk of cancer: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Du Liang, Wang Haichuan, Xiong Tianyuan, Ma Yaxian, Yang Jiqiao, Huang Jichong, Zeng Dong, Wang Xiaoze, Huang He, Huang Jin

Abstract excerpt

Polymorphisms in the MGMT gene have been implicated in susceptibility to cancer, but the published studies have reported inconclusive results. The objective of the current study was to investigate the genetic risk of polymorphisms in the MGMT gene for cancer. A meta-analysis was carried out to analyze the association between polymorphisms in the MGMT gene and cancer risk. Five polymorphisms (Leu84Phe, Leu53Leu,...

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Identifiers

PMID: 23760981
DOI: 10.1007/s13277-013-0893-x

Genes

MGMT

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