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Article

Analysis of Association Between MGMT and p53 Gene Single Nucleotide Polymorphisms and Laryngeal Cancer.

Anticancer research - 1 Aug 2017

Lv Yayun, Jia Chuanliang, Jiang Aihua, Zhang Hua, Wang Yunqiang, Liu Feifei, Yang Linlin, Sun Yan, Lv Runli, Song Xicheng

Abstract excerpt

AIM: To investigate the p53 and O6-methylguanine DNA methyltransferase (MGMT)5' upstream sequence gene promoter regions for single nucleotide polymorphisms and explore the p53 gene 5' upstream sequence consisting of two haplotypes to provide a genetic marker for the incidence of laryngeal squamous cell carcinoma. MATERIALS AND METHODS: We included 96 cases of laryngeal squamous cell carcinoma and 102 controls. We...

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Share to DNA Modification Methylases
Share to DNA Repair Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Association Studies

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Share to Promoter Regions, Genetic

Share to Tumor Suppressor Protein p53

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Source

Identifiers

PMID: 28739733
DOI: 10.21873/anticanres.11834

Genes

MGMT

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