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Article

High prevalence of mutation in the Plasmodium falciparum dhfr and dhps genes in field isolates from Sabah, Northern Borneo.

Malaria journal - 12 Jun 2013

Abdullah Noor Rain, Norahmad Nor Azrina, Jelip Jenarun, Sulaiman Lokman Hakim, Mohd Sidek Hasidah, Ismail Zakiah, Noedl Harald

Abstract excerpt

BACKGROUND: Sulphadoxine-pyrimethamine (SP) has been in use for the treatment of uncomplicated falciparum malaria in Malaysia since the 1970s and is still widely employed in spite of widespread clinical resistance. Resistance to SP is known to be mediated by mutations in the pfdhfr and pfdhps genes. The aim of the present study was to investigate the distribution of pfdhfr and pfdhps gene polymorphism in...

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Source

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Identifiers

PMID: 23758930
DOI: 10.1186/1475-2875-12-198
PMCID: PMC3706343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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