Article
Prevalence of Plasmodium falciparum Molecular Markers of Antimalarial Drug Resistance in a Residual Malaria Focus Area in Sabah, Malaysia.
PloS one - 1 Jan 2016
Norahmad Nor Azrina, Mohd Abd Razak Mohd Ridzuan, Abdullah Noor Rain, Sastu Umi Rubiah, Imwong Mallika, Muniandy Prem Kumar, Saat Muhammad Nor Farhan, Muhammad Amirrudin, Jelip Jenarun, Tikuson Moizin, Yusof Norsalleh, Rundi Christina, Mudin Rose Nani, Syed Mohamed Ami Fazlin
Abstract excerpt
Chloroquine (CQ) and fansidar (sulphadoxine-pyrimethamine, SP) were widely used for treatment of Plasmodium falciparum for several decades in Malaysia prior to the introduction of Artemisinin-based Combination Therapy (ACT) in 2008. Our previous study in Kalabakan, located in south-east coast of Sabah showed a high prevalence of resistance to CQ and SP, suggesting the use of the treatment may no longer be...
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