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Article

Prevalence of the Pfdhfr and Pfdhps mutations among asymptomatic pregnant women in Southeast Nigeria.

Parasitology research - 1 Mar 2018

Esu Ekpereonne, Tacoli Costanza, Gai Prabhanjan, Berens-Riha Nicole, Pritsch Michael, Loescher Thomas, Meremikwu Martin

Abstract excerpt

Sulfadoxine-pyrimethamine (SP) is the recommended drug for intermittent preventive treatment of malaria in pregnancy in most of sub-Saharan Africa. Resistance to SP is related to mutations in the dhfr and dhps gene of Plasmodium falciparum. This study determined the prevalence of Pfdhfr and Pfdhps polymorphisms found in asymptomatic pregnant women attending antenatal care in Calabar, Nigeria. From October 2013 to...

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PMID: 29332155
DOI: 10.1007/s00436-018-5754-5

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