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Article

Comparing somatic mutation-callers: beyond Venn diagrams.

BMC bioinformatics - 10 Jun 2013

Kim Su Yeon, Speed Terence P

Abstract excerpt

BACKGROUND: Somatic mutation-calling based on DNA from matched tumor-normal patient samples is one of the key tasks carried by many cancer genome projects. One such large-scale project is The Cancer Genome Atlas (TCGA), which is now routinely compiling catalogs of somatic mutations from hundreds of paired tumor-normal DNA exome-sequence data. Nonetheless, mutation calling is still very challenging. TCGA benchmark...

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Identifiers

PMID: 23758877
DOI: 10.1186/1471-2105-14-189
PMCID: PMC3702398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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