Article

Accuracy and Reproducibility of Somatic Point Mutation Calling in Clinical-Type Targeted Sequencing Data

2019-12-31

Abstract excerpt

<h4>Background</h4> Treating cancer depends in part on identifying the mutations driving each patient’s disease. Many clinical laboratories are adopting high-throughput sequencing for assaying patients’ tumours, applying targeted panels to formalin-fixed paraffin-embedded tumour tissues to detect clinically-relevant mutations. While there have been some benchmarking and best practices studies of this scenario, mu...

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Literature Corpus work: a168cefc-1cfe-5a55-acc8-929f0494d243
DOI: 10.1101/2019.12.31.891952

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