Article
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Nature communications - 21 Sept 2020
Bailey Matthew H, Meyerson William U, Dursi Lewis Jonathan, Wang Liang-Bo, Dong Guanlan, Liang Wen-Wei, Weerasinghe Amila, Li Shantao, Li Yize, Kelso Sean, Saksena Gordon, Ellrott Kyle, Wendl Michael C, Wheeler David A, Getz Gad, Simpson Jared T, Gerstein Mark B, Ding Li
Abstract excerpt
The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS...
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