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Article

Elevated body mass index as a causal risk factor for symptomatic gallstone disease: a Mendelian randomization study.

Hepatology (Baltimore, Md.) - 1 Dec 2013

Stender Stefan, Nordestgaard Børge G, Tybjaerg-Hansen Anne

Abstract excerpt

UNLABELLED: Elevated body mass index (BMI) is associated with an increased risk of gallstone disease. Whether this reflects a causal association is unknown. Using a Mendelian randomization approach, we studied 77,679 individuals from the general population. Of these, 4,106 developed symptomatic gallstone disease during up to 34 years of follow-up. Subjects were genotyped for three common variants known to...

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Identifiers

PMID: 23775818
DOI: 10.1002/hep.26563

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FTO
TMEM18

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