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Article

HLA peptide length preferences control CD8+ T cell responses.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2013

Rist Melissa J, Theodossis Alex, Croft Nathan P, Neller Michelle A, Welland Andrew, Chen Zhenjun, Sullivan Lucy C, Burrows Jacqueline M, Miles John J, Brennan Rebekah M, Gras Stephanie, Khanna Rajiv, Brooks Andrew G, McCluskey James, Purcell Anthony W, Rossjohn Jamie, Burrows Scott R

Abstract excerpt

Class I HLAs generally present peptides of 8-10 aa in length, although it is unclear whether peptide length preferences are affected by HLA polymorphism. In this study, we investigated the CD8(+) T cell response to the BZLF1 Ag of EBV, which includes overlapping sequences of different size that n...

Read the complete abstract on PubMed

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Share to Binding Sites, Antibody
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

Share to HLA-B44 Antigen

Share to Leukocytes, Mononuclear

Share to Peptide Fragments

Share to Protein Structure, Tertiary

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Source

Identifiers

PMID: 23749632
DOI: 10.4049/jimmunol.1300292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23749632-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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