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Article

Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.

Endocrinology - 1 Aug 2013

Kim Won Gu, Park Jeong Won, Willingham Mark C, Cheng Sheue-yann

Abstract excerpt

Recent epidemiological studies provide strong evidence suggesting obesity is a risk factor in several cancers, including thyroid cancer. However, the molecular mechanisms by which obesity increases the risk of thyroid cancer are poorly understood. In this study, we evaluated the effect of diet-induced obesity on thyroid carcinogenesis in a mouse model that spontaneously develops thyroid cancer...

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Identifiers

PMID: 23748362
DOI: 10.1210/en.2013-1128
PMCID: PMC3713208

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STAT3

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