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Article

The role of AEBP1 in sex-specific diet-induced obesity.

Molecular medicine (Cambridge, Mass.) - 1 Jan 2000

Zhang Lei, Reidy Shannon P, Nicholson Tara E, Lee Hyun-Jeong, Majdalawieh Amin, Webber Chris, Stewart Bruce R, Dolphin Peter, Ro Hyo-Sung

Abstract excerpt

Obesity is an important risk factor for heart disease, diabetes, and certain cancers, but the molecular basis for obesity is poorly understood. The transcriptional repressor AEBP1, which functions as a negative regulator of PTEN through a protein-protein interaction, is highly expressed in the stromal compartment of adipose tissues, including proliferative preadipocytes, and its expression is abolished in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 16307171
DOI: 10.2119/2005-00021.Ro
PMCID: PMC1449517

Genes

AEBP1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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