Article
Interferon-gamma gene diplotype (AA-rs2069716 / AG-rs2069727) may play an important role during secondary outcomes of severe dengue in Brazilian patients.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2023
Bresani-Salvi Cristiane Campello, Morais Clarice Neuenschwander Lins de, Neco Heytor Victor Pereira da Costa, Farias Pablo Cantalice Santos, Pastor André Filipe, Lima Raul Emídio de, Montarroyos Ulisses Ramos, Acioli-Santos Bartolomeu
Abstract excerpt
Dengue is a global and growing health threat, especially in Southeast Asia, West Pacific and South America. Infection by the dengue virus (DENV) results in dengue fever, which can evolve to severe forms. Cytokines, especially interferons, are involved in the immunopathogenesis of dengue fever, and so may influence the disease outcomes. The aim of this study was to investigate the association between severe forms...
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