Article
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.
Nature - 19 Jul 1990
Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Münsterberg A, Vivian N, Goodfellow P, Lovell-Badge R
Abstract excerpt
A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least fi...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Deletion
- Chromosome Mapping
- Cloning, Molecular
- DNA-Binding Proteins
- Female
- Male
- Mice
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Restriction Mapping
- Sequence Homology, Nucleic Acid