Article

A Phylogenetic Profiling Approach Identifies Novel Ciliogenesis Genes In <i>Drosophila</i> And <i>C. elegans</i>

2022-12-29

Abstract excerpt

<h4>SUMMARY</h4> Cilia are cellular projections that perform sensory and motile functions in eukaryotic cells. A defining feature of cilia is that they are evolutionarily ancient yet not universally conserved. In this study we have used the resulting presence and absence pattern in the genomes of diverse eukaryotes to identify a set of 386 human genes associated with cilium assembly or motility. Comprehensive tis...

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Literature Corpus work: d60bf6cb-aabd-5db9-9f5f-fa5cffc24cee
DOI: 10.1101/2022.12.28.522111

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