Article
Systematic discovery of novel ciliary genes through functional genomics in the zebrafish.
Development (Cambridge, England) - 1 Sept 2014
Choksi Semil P, Babu Deepak, Lau Doreen, Yu Xianwen, Roy Sudipto
Abstract excerpt
Cilia are microtubule-based hair-like organelles that play many important roles in development and physiology, and are implicated in a rapidly expanding spectrum of human diseases, collectively termed ciliopathies. Primary ciliary dyskinesia (PCD), one of the most prevalent of ciliopathies, arises from abnormalities in the differentiation or motility of the motile cilia. Despite their biomedical importance, a...
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