Genetic risk factors for venous thromboembolism.

doi:10.1080/17474086.2020.1804354

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Article

Genetic risk factors for venous thromboembolism.

Expert review of hematology - 1 Sept 2020

Zöller Bengt, Svensson Peter J, Dahlbäck Björn, Lind-Hallden Christina, Hallden Christer, Elf Johan

Abstract excerpt

INTRODUCTION: Venous thromboembolism (VTE) is a complex disease that aggregates in families. Both acquired and genetic risk factors are important. Proper recognition and management of high-risk individuals are important. AREAS COVERED: The genetic risk factors for VTE, the clinical consequences, and future perspectives are summarized. Classical thrombophilia i.e., factor V Leiden (rs6025), the prothrombin G20210A...

Topics

Activated Protein C Resistance
Alleles
Animals
Contraceptives, Oral
Disease Models, Animal
Disease Susceptibility
Epistasis, Genetic
Gene Expression
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
High-Throughput Nucleotide Sequencing
Humans
Mutation
Protein C Deficiency
Protein S Deficiency
Risk Factors
Thrombophilia

Source

Open in PubMed

Identifiers

PMID: 32731838
DOI: 10.1080/17474086.2020.1804354

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