Epigenetic regulation of monoallelic gene expression.

doi:10.1111/j.1440-169x.2011.01317.x

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Article

Epigenetic regulation of monoallelic gene expression.

Development, growth & differentiation - 1 Jan 2012

Shiba Hiroshi, Takayama Seiji

Abstract excerpt

Monoallelic expression from biallelic genes is frequently observed in diploid eukaryotic organisms. Classic examples of this phenomenon include the well-characterized cases of genomic imprinting and X-chromosome inactivation. However, recent studies have shown that monoallelic expression is widespread in autosomal genes. This discovery was met with great interest because it represents another mechanism to...

Topics

Alleles
Base Sequence
Brassica
Cell Lineage
DNA Methylation
Gene Expression Profiling
Gene Expression Regulation, Developmental
Gene Silencing
Genomic Imprinting
Humans
Molecular Sequence Data
Phenotype
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid
X Chromosome Inactivation

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Open in PubMed

Identifiers

PMID: 23741751
DOI: 10.1111/j.1440-169x.2011.01317.x

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