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Article

Rac1 selective activation improves retina ganglion cell survival and regeneration.

PloS one - 1 Jan 2013

Lorenzetto Erika, Ettorre Michele, Pontelli Valeria, Bolomini-Vittori Matteo, Bolognin Silvia, Zorzan Simone, Laudanna Carlo, Buffelli Mario

Abstract excerpt

In adult mammals, after optic nerve injury, retinal ganglion cells (RGCs) do not regenerate their axons and most of them die by apoptosis within a few days. Recently, several strategies that activate neuronal intracellular pathways were proposed to prevent such degenerative processes. The rho-rel...

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Identifiers

PMID: 23734197
DOI: 10.1371/journal.pone.0064350
PMCID: PMC3667179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23734197-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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