Article
MR signal amplification for imaging of the mutant EGF receptor in orthotopic human glioma model.
Molecular imaging and biology - 1 Dec 2013
Shazeeb Mohammed Salman, Gupta Suresh, Bogdanov Alexei
Abstract excerpt
PURPOSE: To investigate the potential of targeted MR signal amplification strategy for imaging of EGF receptor variant III (EGFRvIII) overexpression associated with the infiltrating margin of aggressive orthotopic brain tumors. PROCEDURES: F(ab')2 fragments of humanized anti-EGFRvIII monoclonal a...
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