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Development of Integrin α5β1-targeted PET/NIR imaging probes for glioblastoma intraoperative navigation and intracavity targeted radionuclide therapy

2026-01-12

Abstract excerpt

<h4>ABSTRACT</h4> Incomplete extent of tumor resection is the major factor of glioblastoma recurrence, leading to its poor prognosis. Developing therapies that enable the minimal tumor cell remnant during surgical resection is a major challenge to combat this aggressive cancer. This study develops a glioblastoma integrin α5β1-selective peptide binder through series strategy screening and labeling it with 68 Ga,...

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Literature Corpus work
9d0bc08c-67f3-5cde-8b71-8b61da6bc275
DOI
10.64898/2026.01.09.698741
Open publication

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Development of Integrin α5β1-targeted PET/NIR imaging probes for glioblastoma intraoperative navigation and intracavity targeted radionuclide therapyDOI 10.64898/2026.01.09.698741
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