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Article

Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2005

Aghi Manish, Gaviani Paola, Henson John W, Batchelor Tracy T, Louis David N, Barker Fred G

Abstract excerpt

PURPOSE: Two clinical-molecular glioblastoma subtypes have been described: "primary" glioblastomas arise de novo in older patients and often overexpress epidermal growth factor receptor (EGFR); "secondary" glioblastomas progress from lower-grade tumors in younger patients and commonly have TP53 mutations. EGFR overexpression correlates in experimental gliomas with increased angiogenesis, edema, and invasion. No...

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Source

Identifiers

PMID: 16361543
DOI: 10.1158/1078-0432.CCR-05-0713

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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