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Article

Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes.

Molecular genetics and metabolism - 1 May 2011

Kure Masahiko, Pezzolesi Marcus G, Poznik G David, Katavetin Pisut, Skupien Jan, Dunn Jonathon S, Mychaleckyj Josyf C, Warram James H, Krolewski Andrzej S

Abstract excerpt

Genetic data support the notion that polymorphisms in members of the matrix metalloproteinase (MMP) family of genes play an important role in extracellular matrix remodeling and contribute to the pathogenesis of vascular disease. To identify novel genetic markers for diabetic nephropathy (DN), we examined the relationship between MMP gene polymorphisms and DN in the Genetics of Kidneys in Diabetes (GoKinD)...

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Identifiers

PMID: 21277817
DOI: 10.1016/j.ymgme.2011.01.001
PMCID: PMC3081941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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