Article
Hyperuricemia contributes to the faster progression of diabetic kidney disease in type 2 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
Bartáková Vendula, Kuricová Katarína, Pácal Lukáš, Nová Zuzana, Dvořáková Veronika, Švrčková Martina, Malúšková Denisa, Svobodová Ivana, Řehořová Jitka, Svojanovský Jan, Olšovský Jindřich, Bělobrádková Jana, Kaňková Kateřina
Abstract excerpt
AIMS: The aims of the study were (i) to ascertain prognostic value of serum uric acid (SUA) for diabetic kidney disease (DKD) progression and major adverse cardiovascular event (MACE) in a cohort of T2DM patients, (ii) to ascertain eventual protective effect of allopurinol treatment, (iii) to determine the effect of genetic variability in UA transporters on DKD progression, and (iv) to define optimal cut-off...
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